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SPS

ANDA

SODIUM POLYSTYRENE SULFONATE | A087859 | CMP PHARMA INC

1 strength0 unique patents0 unique exclusivities

Drug Pricing (NADAC)

National Average Drug Acquisition Cost — Week of 2026-07-15 | 2 NDCs

Highest NADAC/Unit

$0.4335

per ml

Lowest NADAC/Unit

$0.3851

per ml

Brand NDCs

Generic NDCs

NDC Description	NADAC/Unit	Unit	Type	Generic NADAC	Effective
46287000601SPS 15 GM/60 ML SUSPENSION	$0.4335	ML	Generic	—	2026-06-17
46287000660SPS 15 GM/60 ML SUSPENSION	$0.3851	ML	Generic	—	2026-04-22

Source: NADAC (data.medicaid.gov). Prices reflect national average acquisition costs for retail community pharmacies.

VA Federal Supply Schedule

Government-negotiated contract prices | 2 NDCs (2 FSS)

Lowest Price

$164.78

Highest Price

$223.56

FSS NDCs

Big4 NDCs

Description	Price	Type	Vendor	Contract End
46287-0006-01SODIUM POLYSTYRENE SULFONATE 15GM/60ML SUSP	$164.78	FSS	CMP Pharma	07/14/2026
46287-0006-60SODIUM POLYSTYRENE SULFONATE 15GM/60ML SUSP,6	$223.56	FSS	CMP Pharma	07/14/2026

Source: VA Federal Supply Schedule (va.gov). Prices are government-negotiated contract prices.

Medicare Part D Spending

CMS annual spending data for Sps (2024)

Total Spending

$13.6M

Total Claims

100,224

Beneficiaries

55,768

Avg Cost/Unit

$0.41

Spending Trend

$3.8M(2019)→$8.3M(2020)→$11.1M(2021)→$11.6M(2022)→$13.6M(2023)→$13.6M(2024)

YoY Change:+5.2%

5yr CAGR:+16.0%

Source: CMS Medicare Part D Spending by Drug (2024). Shows gross drug cost under Part D.

API Supply Chain2 active DMFs

2 active API suppliers hold Drug Master Files for this ingredient. Limited supplier base — potential supply chain risk.

PUROLITE LLCSODIUM POLYSTYRENE SULFONATE

DMF 58821985

ION EXCHANGE INDIA LTDSODIUM POLYSTYRENE SULFONATE USP (INDION 254)

DMF 183642005

Source: FDA Drug Master Files (fda.gov). Type II API DMFs matched by ingredient.

Products (1)

#001 — 15GM/60ML

RLDAA

0 patents0 exclusivities▴

SUSPENSION;ORAL, RECTAL | Approved: Dec 8, 1982

No patent or exclusivity listings for this strength.