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METOPROLOL SUCCINATE

ANDA

METOPROLOL SUCCINATE | A204161 | ACTAVIS ELIZABETH LLC

4 strengths0 unique patents0 unique exclusivities

Reference Listed Drug: TOPROL-XL(TE code: AB)

Drug Pricing (NADAC)

National Average Drug Acquisition Cost — Week of 2026-07-15 | 7 NDCs

Highest NADAC/Unit

$0.1714

per ea

Lowest NADAC/Unit

$0.0555

per ea

Brand NDCs

Generic NDCs

NDC Description	NADAC/Unit	Unit	Type	Generic NADAC	Effective
45963067811METOPROLOL SUCC ER 200 MG TAB	$0.1714	EA	Generic	—	2026-06-17
45963067711METOPROLOL SUCC ER 100 MG TAB	$0.0906	EA	Generic	—	2026-06-17
45963067796METOPROLOL SUCC ER 100 MG TAB	$0.0906	EA	Generic	—	2026-06-17
45963067611METOPROLOL SUCC ER 50 MG TAB	$0.0579	EA	Generic	—	2026-06-17
45963067696METOPROLOL SUCC ER 50 MG TAB	$0.0579	EA	Generic	—	2026-06-17
45963070911METOPROLOL SUCC ER 25 MG TAB	$0.0555	EA	Generic	—	2026-06-17
45963070996METOPROLOL SUCC ER 25 MG TAB	$0.0555	EA	Generic	—	2026-06-17

Source: NADAC (data.medicaid.gov). Prices reflect national average acquisition costs for retail community pharmacies.

VA Federal Supply Schedule

Government-negotiated contract prices | 7 NDCs (7 FSS)

Lowest Price

$14.23

Highest Price

$217.28

FSS NDCs

Big4 NDCs

Description	Price	Type	Vendor	Contract End
45963-0676-11METOPROLOL SUCCINATE 50MG TAB,SA	$14.23	FSS	AvKare, LLC	06/14/2028
45963-0676-96METOPROLOL SUCCINATE 50MG TAB,SA	$113.89	FSS	AvKare, LLC	06/14/2028
45963-0677-11METOPROLOL SUCCINATE 100MG TAB,SA	$36.02	FSS	AvKare, LLC	06/14/2028
45963-0677-96METOPROLOL SUCCINATE 100MG TAB,SA	$217.28	FSS	AvKare, LLC	06/14/2028
45963-0678-11METOPROLOL SUCCINATE 200MG TAB,SA	$57.32	FSS	AvKare, LLC	06/14/2028
45963-0709-11METOPROLOL SUCCINATE 25MG TAB,SA	$23.97	FSS	AvKare, LLC	06/14/2028
45963-0709-96METOPROLOL SUCCINATE 25MG TAB,SA	$143.82	FSS	AvKare, LLC	06/14/2028

Source: VA Federal Supply Schedule (va.gov). Prices are government-negotiated contract prices.

API Supply Chain26 active DMFs12 inactive

25 active API suppliers hold Drug Master Files for this ingredient.

TAPI NL BVMETOPROLOL SUCCINATE

DMF 146121999

MOEHS IBERICA SLMETOPROLOL SUCCINATE

DMF 166212003

DR REDDYS LABORATORIES LTDMETOPROLOL SUCCINATE USP

DMF 183482005

APITORIA PHARMA PRIVATE LTDMETOPROLOL SUCCINATE USP

DMF 192812006

ZHEJIANG APELOA JIAYUAN PHARMACEUTICAL CO LTDMETOPROLOL SUCCINATE USP

DMF 195682006

IPCA LABORATORIES LTDMETOPROLOL SUCCINATE USP (PROCESS-II)

DMF 196382006

ZYDUS LIFESCIENCES LTDMETOPROLOL SUCCINATE USP

DMF 197602006

ZHEJIANG HISOAR PHARMACEUTICAL CO LTDMETOPROLOL SUCCINATE

DMF 214542008

ALEMBIC PHARMACEUTICALS LTDMETOPROLOL SUCCINATE USP

DMF 215102008

CTX LIFE SCIENCES PVT LTDMETOPROLOL SUCCINATE USP

DMF 217322008

YUNG ZIP CHEMICAL IND CO LTDMETOPROLOL SUCCINATE

DMF 246572011

ZHEJIANG HUAHAI PHARMACEUTICAL CO LTDMETOPROLOL SUCCINATE USP

DMF 268042013

HEC PHARM CO LTDMETOPROLOL SUCCINATE NON-STERILE BULK DRUG SUBSTANCE

DMF 279152014

ZHEJIANG YONGTAI PHARMACEUTICAL CO LTDMETOPROLOL SUCCINATE USP

DMF 299542015

ASTRAZENECA PHARMACEUTICALS LPMETOPROLOL SUCCINATE EXTENDED RELEASE TABLETS

DMF 311402016

SUN PHARMACEUTICAL INDUSTRIES LTDMETOPROLOL SUCCINATE USP

DMF 314532017

UNICHEM LABORATORIES LTDMETOPROLOL SUCCINATE USP

DMF 325252018

YUNG ZIP CHEMICAL IND CO LTDMETOPROLOL SUCCINATE (PROCESS II)

DMF 332022018

MACLEODS PHARMACEUTICALS LTDMETOPROLOL SUCCINATE

DMF 333292019

GRANULES INDIA LTDMETOPROLOL SUCCINATE USP

DMF 335442019

HETERO DRUGS LTDMETOPROLOL SUCCINATE

DMF 336242019

MSN LIFE SCIENCES PRIVATE LTDMETOPROLOL SUCCINATE USP

DMF 347062020

INDOCO REMEDIES LTDMETOPROLOL SUCCINATE USP

DMF 348902020

KOPRAN RESEARCH LABORATORIES LTDMETOPROLOL SUCCINATE USP

DMF 351102020

GRANULES PHARMACEUTICALS INCMETOPROLOL SUCCINATE MICROSPHERES 90% W/W

DMF 359592021

ATUL BIOSCIENCE LTDMETOPROLOL SUCCINATE USP

DMF 420422025

ESTEVE QUIMICA SAInactiveMETOPROLOL SUCCINATE

DMF 105471993

ZENTIVA KSInactiveMETOPROLOL SUCCINATE

DMF 116001995

SYN-TECH CHEM AND PHARM CO LTDInactiveMETOPROLOL SUCCINATE USP

DMF 159662002

MEDICHEM SAInactiveMETOPROLOL SUCCINATE

DMF 170192003

IPCA LABORATORIES LTDInactiveMETOPROLOL SUCCINATE

DMF 170562003

AARTI DRUGS LTDInactiveMETOPROLOL SUCCINATE

DMF 194902006

ZAKLADY FARMACEUTYCZNE POLPHARMA SAInactiveMETOPROLOL SUCCINATE

DMF 197432006

SUN PHARMACEUTICAL INDUSTRIES LTDInactiveMETOPROLOL SUCCINATE USP

DMF 206462007

AREVIPHARMA GMBHInactiveMetoprolol Succinate

DMF 211552007

POLYDRUG LABORATORIES PVT LTDInactiveMETOPROLOL SUCCINATE

DMF 218842008

TEVA PHARMACEUTICAL INDUSTRIES LTDInactiveMETOPROLOL SUCCINATE USP

DMF 219792008

ASTRAZENECA PHARMACEUTICALS LPInactiveMETOPROLOL SUCCINATE EXTENDED RELEASE/HYDROCHLOROTHIAZIDE 25/12.5,50/12.5 AND100/12.5 TABLETS

DMF 282062014

Source: FDA Drug Master Files (fda.gov). Type II API DMFs matched by ingredient.

Products (4)

Sort:

#001 — EQ 25MG TARTRATE

0 patents0 exclusivities▴

TABLET, EXTENDED RELEASE;ORAL | Approved: Nov 25, 2016

No patent or exclusivity listings for this strength.

#002 — EQ 50MG TARTRATE

0 patents0 exclusivities▾

TABLET, EXTENDED RELEASE;ORAL | Approved: Nov 25, 2016

#003 — EQ 100MG TARTRATE

0 patents0 exclusivities▾

TABLET, EXTENDED RELEASE;ORAL | Approved: Nov 25, 2016

#004 — EQ 200MG TARTRATE

0 patents0 exclusivities▾

TABLET, EXTENDED RELEASE;ORAL | Approved: Nov 25, 2016